Efficacy and Safety of Letibotulinum Toxin A for the Treatment of Melasma in Two Different Dilutions: A Randomized Double-Blind Split-Face Study

Background: Melasma is an acquired hyperpigmentation disorder with multifactorial etiologies and limited response to conventional therapies. Recent evidence suggests that Botulinum Toxin A (BoNT-A) may modulate ultraviolet (UV)-induced pigmentation and offer therapeutic benefits. Objective: We sough...

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Main Authors: Juthapa Pongklaokam, Woraphong Manuskiatti, Rungsima Wanitphakdeedecha, Pitchaya Maneeprasopchoke, Panwadee Thongjaroensirikul, Yanin Nokdhes, Rona Maria R. Abad-Constantino, Woramate Bhorntarakcharoen, Sariya Sittiwanaruk, Thanya Techapichetvanich
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Toxins
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Online Access:https://www.mdpi.com/2072-6651/17/7/349
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