Naringin mitigated doxorubicin-induced kidney injury by the reduction of oxidative stress and inflammation with a synergistic anticancer effect

Naringin mitigated doxorubicin-induced kidney injury by the reduction of oxidative stress and inflammation with a synergistic anticancer effect

Abstract Background The pathophysiology and severity of kidney impairment due to doxorubicin (DOX) treatment are markedly influenced by oxidative stress and inflammation. Naringin (NG), a natural flavonoid, has anti-inflammatory and antioxidant properties. The nephroprotective effect of NG on DOX-in...

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Bibliographic Details
Main Authors: Nahla S. Gad, Sameh M. Shabana, Maggie E. Amer, Azza I. Othman, Mohamed A. El-Missiry
Format: Article
Language:English
Published: BMC 2025-06-01
Series:BMC Pharmacology and Toxicology
Subjects:
Naringin
Doxorubicin
Kidney injury
Antioxidants
Inflammation
Kidney histopathology
Online Access:https://doi.org/10.1186/s40360-025-00947-7
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https://doi.org/10.1186/s40360-025-00947-7

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