Mechanisms of resistance to CAR-T cell therapy in multiple myeloma: latest updates from the 2024 ASH annual meeting

Abstract Chimeric Antigen Receptor T-Cell (CAR-T) therapy demonstrates significant potential in the treatment of multiple myeloma (MM). However, resistance to CAR-T therapy remains a critical challenge. Investigating the mechanisms underlying CAR-T resistance, including antigen escape, immunosuppres...

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Bibliographic Details
Main Authors: Yuhan Hu, Jiangxue Hou, Zhongxing Jiang, Quande Lin
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Experimental Hematology & Oncology
Subjects:
Online Access:https://doi.org/10.1186/s40164-025-00643-6
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