Immune Escape and Drug Resistance Mutations in Patients with Hepatitis B Virus Infection: Clinical and Epidemiological Implications

Immune Escape and Drug Resistance Mutations in Patients with Hepatitis B Virus Infection: Clinical and Epidemiological Implications

Hepatitis B virus (HBV) genetic variability, shaped by high mutation rates and selective pressures, complicates its management and increases the emergence of drug-resistant and immune-escape variants. This study aims to analyze immune escape mutations (IEMs) and drug resistance mutations (DRMs) in p...

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Main Authors: Maria Antonia De Francesco, Franco Gargiulo, Francesca Dello Iaco, Laert Zeneli, Serena Zaltron, Giorgio Tiecco, Simone Pellizzeri, Emanuele Focà, Arnaldo Caruso, Eugenia Quiros-Roldan
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Life
Subjects:
HBV
escape mutations
drug resistance mutations
genotypes
vaccine
sequence
Online Access:https://www.mdpi.com/2075-1729/15/4/672
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https://www.mdpi.com/2075-1729/15/4/672

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