Scintillation proximity assay for DNA binding by human p53

Many DNA binding proteins are known to regulate gene expression. When that binding is altered, a disease state can result. A common method for measuring DNA binding, namely electrophoretic mobility shift assay (EMSA) is often used but it is not amenable to rapid screening of many samples. As an alte...

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Bibliographic Details
Main Authors: Susannah Gal, Jeffery R. Cook, Leighton Howells
Format: Article
Language:English
Published: Taylor & Francis Group 2006-09-01
Series:BioTechniques
Online Access:https://www.future-science.com/doi/10.2144/000112222
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