Lidocaine Affects Collagen Breakdown Without Compromising Cell Viability in Cultured Human Tenocytes: An In Vitro Study

Lidocaine Affects Collagen Breakdown Without Compromising Cell Viability in Cultured Human Tenocytes: An In Vitro Study

Local anesthetics (LAs) are frequently administered via peritendinous ultrasound-guided injections for diagnostic and therapeutic purposes. Since in vitro studies have demonstrated LAs’ tenotoxic effects, raising concerns about their safety in infiltrative treatments, and since lidocaine (LD) emerge...

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Bibliographic Details
Main Authors: Filippo Randelli, Manuel G. Mazzoleni, Alessandra Menon, Alberto Fioruzzi, Dolaji Henin, Michele Sommariva, Nicoletta Gagliano
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Cells
Subjects:
lidocaine injection
tendinopathy
infiltration
tendon
tenocytes
apoptosis
Online Access:https://www.mdpi.com/2073-4409/14/13/988
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