Characterization of 3,3′-iminodipropionitrile (IDPN) damaged utricle transcriptome in the adult mouse utricle

Characterization of 3,3′-iminodipropionitrile (IDPN) damaged utricle transcriptome in the adult mouse utricle

Utricle is an important vestibular sensory organ for maintaining balance. 3,3′-iminodipropionitrile (IDPN), a prototype nitrile toxin, has been reported to be neurotoxic and vestibulotoxic, and can be used to establish an in vivo damage model of vestibular dysfunction. However, the mechanism of utri...

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Bibliographic Details
Main Authors: Mengyao Tian, Jingyuan Huang, Hairong Xiao, Pei Jiang, Xiangyu Ma, Yanqin Lin, Xujun Tang, Yintao Wang, Mingchen Dai, Wei Tong, Zixuan Ye, Xia Sheng, Renjie Chai, Shasha Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Molecular Neuroscience
Subjects:
utricle
IDPN
RNA-seq
neomycin
hair cell damage
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2024.1487364/full
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https://www.frontiersin.org/articles/10.3389/fnmol.2024.1487364/full

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