Integrated analysis of single-cell and bulk RNA-sequencing to predict prognosis and therapeutic response for colorectal cancer

Integrated analysis of single-cell and bulk RNA-sequencing to predict prognosis and therapeutic response for colorectal cancer

Abstract Colorectal cancer (CRC) is a prevalent malignant tumor characterized by high global incidence and mortality rates. Furthermore, it is imperative to comprehend the molecular mechanisms underlying its development and to identify effective prognostic markers. These efforts are crucial for pinp...

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Bibliographic Details
Main Authors: Liyang Cai, Xin Guo, Yucheng Zhang, Huajie Xie, Yongfeng Liu, Jianlong Zhou, Huolun Feng, Jiabin Zheng, Yong Li
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
Colorectal cancer
Prognostic model
scRNA-seq
Epithelial cell marker genes
Online Access:https://doi.org/10.1038/s41598-025-91761-y
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https://doi.org/10.1038/s41598-025-91761-y

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