Do patients regret having in-office vocal fold injections for glottic insufficiency?
Abstract Background In-office vocal fold injections (VFI) are an effective treatment for glottic insufficiency. The primary objective of this study was to assess if patients reported decisional regret after VFI. Secondary objectives included determining if variables were associated with lower decisi...
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SAGE Publishing
2023-04-01
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Series: | Journal of Otolaryngology - Head and Neck Surgery |
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Online Access: | https://doi.org/10.1186/s40463-023-00643-8 |
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author | Alice Q. Liu Yunqi Ji Amanda Hu |
author_facet | Alice Q. Liu Yunqi Ji Amanda Hu |
author_sort | Alice Q. Liu |
collection | DOAJ |
description | Abstract Background In-office vocal fold injections (VFI) are an effective treatment for glottic insufficiency. The primary objective of this study was to assess if patients reported decisional regret after VFI. Secondary objectives included determining if variables were associated with lower decisional regret. Methods Case–control study of patients who underwent in-office VFIs for glottic insufficiency from August 2017 to December 2019 at a tertiary laryngology clinic. Participants completed the validated Decision Regret Scale (DRS). Demographic data, clinician’s perceptual analysis with GRBAS (Grade, Roughness, Breathiness, Asthenia, Strain), and patient’s self-reported Voice Handicap Index-10 (VHI-10) were analyzed. Nonparametric tests as well as univariate and multiple logistics regression were performed. Results Of patients eligible, 75% (136/182) completed the DRS (mean age 65.4 years (SD 13.9), 58.1% male). Eighty-three (61.0%) reported no decisional regret, thirty-three (24.3%) reported mild decisional regret, and twenty (14.7%) reported moderate to strong decisional regret. Improvement in most recent VHI-10 (Kendall correlation coefficient tau = 0.156, p = 0.029), Grade of voice (tau = 0.236, p value = 0.002) and Breathiness of voice (tau = 0.150, p = 0.044) were associated with lower DRS. Multivariate logistics regression results showed that the change in Grade of voice (OR 9.9, p < 0.01), Roughness (OR 0.2, p < 0.01) and Breathiness (OR 0.2, p < 0.03) were significantly associated with DRS. Conclusion The majority of patients had no or mild decisional regret after in-office VFI for glottic insufficiency. Both patients who reported less vocal handicap after VFI and clinician-noted improvements in perceptual evaluation of voice after VFI were associated with significantly lower decisional regret. Graphical Abstract |
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language | English |
publishDate | 2023-04-01 |
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spelling | doaj-art-3dd2a3ad38ca4402ac2b128da0156db32025-02-03T11:13:51ZengSAGE PublishingJournal of Otolaryngology - Head and Neck Surgery1916-02162023-04-0152111110.1186/s40463-023-00643-8Do patients regret having in-office vocal fold injections for glottic insufficiency?Alice Q. Liu0Yunqi Ji1Amanda Hu2Division of Otolaryngology-Head and Neck Surgery, University of British ColumbiaDepartment of Community Health Sciences, University of CalgaryDivision of Otolaryngology-Head and Neck Surgery, University of British ColumbiaAbstract Background In-office vocal fold injections (VFI) are an effective treatment for glottic insufficiency. The primary objective of this study was to assess if patients reported decisional regret after VFI. Secondary objectives included determining if variables were associated with lower decisional regret. Methods Case–control study of patients who underwent in-office VFIs for glottic insufficiency from August 2017 to December 2019 at a tertiary laryngology clinic. Participants completed the validated Decision Regret Scale (DRS). Demographic data, clinician’s perceptual analysis with GRBAS (Grade, Roughness, Breathiness, Asthenia, Strain), and patient’s self-reported Voice Handicap Index-10 (VHI-10) were analyzed. Nonparametric tests as well as univariate and multiple logistics regression were performed. Results Of patients eligible, 75% (136/182) completed the DRS (mean age 65.4 years (SD 13.9), 58.1% male). Eighty-three (61.0%) reported no decisional regret, thirty-three (24.3%) reported mild decisional regret, and twenty (14.7%) reported moderate to strong decisional regret. Improvement in most recent VHI-10 (Kendall correlation coefficient tau = 0.156, p = 0.029), Grade of voice (tau = 0.236, p value = 0.002) and Breathiness of voice (tau = 0.150, p = 0.044) were associated with lower DRS. Multivariate logistics regression results showed that the change in Grade of voice (OR 9.9, p < 0.01), Roughness (OR 0.2, p < 0.01) and Breathiness (OR 0.2, p < 0.03) were significantly associated with DRS. Conclusion The majority of patients had no or mild decisional regret after in-office VFI for glottic insufficiency. Both patients who reported less vocal handicap after VFI and clinician-noted improvements in perceptual evaluation of voice after VFI were associated with significantly lower decisional regret. Graphical Abstracthttps://doi.org/10.1186/s40463-023-00643-8Vocal fold injectionsVocal fold paralysisVoice handicap indexPatient reported outcomesDecision regret scale |
spellingShingle | Alice Q. Liu Yunqi Ji Amanda Hu Do patients regret having in-office vocal fold injections for glottic insufficiency? Journal of Otolaryngology - Head and Neck Surgery Vocal fold injections Vocal fold paralysis Voice handicap index Patient reported outcomes Decision regret scale |
title | Do patients regret having in-office vocal fold injections for glottic insufficiency? |
title_full | Do patients regret having in-office vocal fold injections for glottic insufficiency? |
title_fullStr | Do patients regret having in-office vocal fold injections for glottic insufficiency? |
title_full_unstemmed | Do patients regret having in-office vocal fold injections for glottic insufficiency? |
title_short | Do patients regret having in-office vocal fold injections for glottic insufficiency? |
title_sort | do patients regret having in office vocal fold injections for glottic insufficiency |
topic | Vocal fold injections Vocal fold paralysis Voice handicap index Patient reported outcomes Decision regret scale |
url | https://doi.org/10.1186/s40463-023-00643-8 |
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