Human coronavirus dependency on host heat shock protein 90 reveals an antiviral target

Human coronavirus dependency on host heat shock protein 90 reveals an antiviral target

Rapid accumulation of viral proteins in host cells render viruses highly dependent on cellular chaperones including heat shock protein 90 (Hsp90). Three highly pathogenic human coronaviruses, including MERS-CoV, SARS-CoV and SARS-CoV-2, have emerged in the past 2 decades. However, there is no approv...

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Bibliographic Details
Main Authors: Cun Li, Hin Chu, Xiaojuan Liu, Man Chun Chiu, Xiaoyu Zhao, Dong Wang, Yuxuan Wei, Yuxin Hou, Huiping Shuai, Jianpiao Cai, Jasper Fuk-Woo Chan, Jie Zhou, Kwok Yung Yuen
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Emerging Microbes and Infections
Subjects:
Coronavirus
Hsp90β
SARS-CoV-2
nucleoprotein
viral replication
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2020.1850183
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https://www.tandfonline.com/doi/10.1080/22221751.2020.1850183

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