Lactic acid inhibits melanin synthesis by regulating histone H3 lactylation and suppressing tyrp1 transcription in B16 melanoma cells
Abstract Lactic acid, a widely distributed metabolic intermediate, exhibits superior permeability and mild acidity, making it a common reagent in skincare products. Lactic acid could significantly reduce melanin synthesis both in vitro and in vivo. However, the underlying molecular mechanisms remain...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
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| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-04225-8 |
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