Immunoproteasome Inhibition Impairs Differentiation but Not Survival of T Helper 17 Cells

Autoimmune and inflammatory diseases are characterized by aberrant immune responses. The immunoproteasome was proposed as a target for such Th cell-mediated diseases due to its role in the activation, differentiation and function of T cells. Even though many studies demonstrated reductions in Th17 c...

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Bibliographic Details
Main Authors: Franziska Oliveri, Dennis Mink, Tony Muchamuel, Michael Basler
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/14/10/689
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