Vector for Pop-In/Pop-Out Gene Replacement in Pichia pastoris

Gene replacement in yeast is often accomplished by using a counterselectable marker such as URA3. Although ura3 strains of Pichia pastoris have been generated, these strains are inconvenient to work with because they grow slowly, even in the presence of uracil. To overcome this limitation, we have d...

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Bibliographic Details
Main Authors: Jon Soderholm, Brooke J. Bevis, Benjamin S. Glick
Format: Article
Language:English
Published: Taylor & Francis Group 2001-08-01
Series:BioTechniques
Online Access:https://www.future-science.com/doi/10.2144/01312st01
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