Gelsolin Facilitates Estrogen Receptor Beta Nuclear Translocation and Transcriptional Repression of Genes Associated with Alzheimer Disease

Gelsolin Facilitates Estrogen Receptor Beta Nuclear Translocation and Transcriptional Repression of Genes Associated with Alzheimer Disease

<b>Background/Objectives</b>: Gelsolin (GSN) is an actin-binding protein that helps maintain neuronal structure and shape, regulates neuronal growth, and apoptosis. Our previous work demonstrated that GSN associated with estrogen receptor beta (ERβ1) in the brains of female rats, but thi...

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Bibliographic Details
Main Authors: Yoldas Yildiz, Angela H. S. Fan, Amanda A. Hartoun, Sarah Flury, Yan Ngai, Toni R. Pak
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Receptors
Subjects:
ESR2
cytoskeleton
nuclear receptor
aging
brain
neuron
Online Access:https://www.mdpi.com/2813-2564/4/2/10
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