Single-Cell RNA Sequencing on Formalin-Fixed and Paraffin-Embedded (FFPE) Tissue Identified Multi-Ciliary Cells in Breast Cancer

Single-Cell RNA Sequencing on Formalin-Fixed and Paraffin-Embedded (FFPE) Tissue Identified Multi-Ciliary Cells in Breast Cancer

The purpose of this study was to evaluate the suitability of formalin-fixed and paraffin-embedded (FFPE) samples and fixed fresh (FF) samples for single-cell RNA sequencing (scRNAseq). To this end, we compared single-cell profiles from FFPE and matched FF tissue samples of one invasive carcinoma of...

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Bibliographic Details
Main Authors: Silvia González-Martínez, José Palacios, Irene Carretero-Barrio, Val F. Lanza, Mónica García-Cosío Piqueras, Tamara Caniego-Casas, David Hardisson, Isabel Esteban-Rodríguez, Javier Cortés, Belén Pérez-Mies
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Cells
Subjects:
single-cell RNA sequencing
breast cancer
multi-ciliated cells
fixed fresh tissue
FFPE tissue
tumor heterogeneity
Online Access:https://www.mdpi.com/2073-4409/14/3/197
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https://www.mdpi.com/2073-4409/14/3/197

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