AKAP12 mediates barrier functions of fibrotic scars during CNS repair.

AKAP12 mediates barrier functions of fibrotic scars during CNS repair.

The repair process after CNS injury shows a well-organized cascade of three distinct stages: inflammation, new tissue formation, and remodeling. In the new tissue formation stage, various cells migrate and form the fibrotic scar surrounding the lesion site. The fibrotic scar is known as an obstacle...

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Main Authors: Jong-Ho Cha, Hee-Jun Wee, Ji Hae Seo, Bum Ju Ahn, Ji-Hyeon Park, Jun-Mo Yang, Sae-Won Lee, Eun Hee Kim, Ok-Hee Lee, Ji Hoe Heo, Hyo-Jong Lee, Irwin H Gelman, Ken Arai, Eng H Lo, Kyu-Won Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0094695&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0094695&type=printable

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