Corynoxeine Supplementation Ameliorates Colistin-Induced Kidney Oxidative Stress and Inflammation in Mice

Corynoxeine Supplementation Ameliorates Colistin-Induced Kidney Oxidative Stress and Inflammation in Mice

This study investigated the protective effects of corynoxeine, a natural alkaline compound, on colistin-caused nephrotoxicity using a murine model. Forty mice were divided randomly into control, corynoxeine-only (20 mg/kg/day, intraperitoneal injection), colistin-only (20 mg/kg/day, intraperitoneal...

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Bibliographic Details
Main Authors: Yue Liu, Ruichen Zhang, Tony Velkov, Jianzhong Shen, Shusheng Tang, Chongshan Dai
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Antioxidants
Subjects:
colistin
nephrotoxicity
corynoxeine
oxidative stress
inflammatory response
Online Access:https://www.mdpi.com/2076-3921/14/5/593
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