Age-period-cohort analysis of self-harm incidence rates by gender in Iran among individuals aged 10–39 years, 1990–2019

Abstract This study investigates trends and patterns in self-harm incidence rates among individuals aged 10–39 years in Iran from 1990 to 2019. Using Age-Period-Cohort (APC) analysis, it aims to identify significant age, period, and cohort effects, and to highlight gender-specific trends for effecti...

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Main Authors: Yousef Ramazani, Alireza Abdi, Shahab Rezaeian, Farid Najafi, Zhyla Aliyavari, Mehdi Moradinazar
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-85861-y
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author Yousef Ramazani
Alireza Abdi
Shahab Rezaeian
Farid Najafi
Zhyla Aliyavari
Mehdi Moradinazar
author_facet Yousef Ramazani
Alireza Abdi
Shahab Rezaeian
Farid Najafi
Zhyla Aliyavari
Mehdi Moradinazar
author_sort Yousef Ramazani
collection DOAJ
description Abstract This study investigates trends and patterns in self-harm incidence rates among individuals aged 10–39 years in Iran from 1990 to 2019. Using Age-Period-Cohort (APC) analysis, it aims to identify significant age, period, and cohort effects, and to highlight gender-specific trends for effective prevention strategies. Utilizing data from the Global Burden of Disease (GBD) study, we performed an APC analysis to assess trends in self-harm incidence rates by gender. Data was stratified into six age groups and six five-year periods, and analyzed using the APC Web Tool from the National Cancer Institute. The average incidence rates of self-harm attempts and deaths among individuals aged 10–39 years were 93.87 and 7.55 per 100,000 individuals, respectively. Females had 1.75 times higher attempt rates than males, while males had 1.62 times higher death rates. The APC analysis revealed that males experienced stable self-harm rates over time, while females showed a significant decline. Peak incidence for both genders occurred at age 22.5 years. Self-harm incidence rates show younger females are more vulnerable to self-harm, but there has been a general decline in incidences over time, particularly for more recent cohorts but the stability of rates across ages and the lower rates in more recent cohorts highlighted in male.
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spelling doaj-art-3d5aabe175d541d8924578f406c069f62025-01-19T12:19:43ZengNature PortfolioScientific Reports2045-23222025-01-011511810.1038/s41598-025-85861-yAge-period-cohort analysis of self-harm incidence rates by gender in Iran among individuals aged 10–39 years, 1990–2019Yousef Ramazani0Alireza Abdi1Shahab Rezaeian2Farid Najafi3Zhyla Aliyavari4Mehdi Moradinazar5Family Health and Population Growth Research Center, Health Institute, Kermanshah University of Medical SciencesEmergency and critical care nursing department,nursing and midwifery school, Kermanshah University of medical sciencesDepartment of Epidemiology, Research Center for Environmental Determinants of Health (RCEDH), Kermanshah University of Medical SciencesDepartment of Epidemiology, Research Center for Environmental Determinants of Health (RCEDH), Kermanshah University of Medical SciencesBehavioral Disease Research Center, Kermanshah University of Medical SciencesFamily Health and Population Growth Research Center, Health Institute, Kermanshah University of Medical SciencesAbstract This study investigates trends and patterns in self-harm incidence rates among individuals aged 10–39 years in Iran from 1990 to 2019. Using Age-Period-Cohort (APC) analysis, it aims to identify significant age, period, and cohort effects, and to highlight gender-specific trends for effective prevention strategies. Utilizing data from the Global Burden of Disease (GBD) study, we performed an APC analysis to assess trends in self-harm incidence rates by gender. Data was stratified into six age groups and six five-year periods, and analyzed using the APC Web Tool from the National Cancer Institute. The average incidence rates of self-harm attempts and deaths among individuals aged 10–39 years were 93.87 and 7.55 per 100,000 individuals, respectively. Females had 1.75 times higher attempt rates than males, while males had 1.62 times higher death rates. The APC analysis revealed that males experienced stable self-harm rates over time, while females showed a significant decline. Peak incidence for both genders occurred at age 22.5 years. Self-harm incidence rates show younger females are more vulnerable to self-harm, but there has been a general decline in incidences over time, particularly for more recent cohorts but the stability of rates across ages and the lower rates in more recent cohorts highlighted in male.https://doi.org/10.1038/s41598-025-85861-yAPC analysisSelf-harmTrendsSuicideIncidence ratesIran
spellingShingle Yousef Ramazani
Alireza Abdi
Shahab Rezaeian
Farid Najafi
Zhyla Aliyavari
Mehdi Moradinazar
Age-period-cohort analysis of self-harm incidence rates by gender in Iran among individuals aged 10–39 years, 1990–2019
Scientific Reports
APC analysis
Self-harm
Trends
Suicide
Incidence rates
Iran
title Age-period-cohort analysis of self-harm incidence rates by gender in Iran among individuals aged 10–39 years, 1990–2019
title_full Age-period-cohort analysis of self-harm incidence rates by gender in Iran among individuals aged 10–39 years, 1990–2019
title_fullStr Age-period-cohort analysis of self-harm incidence rates by gender in Iran among individuals aged 10–39 years, 1990–2019
title_full_unstemmed Age-period-cohort analysis of self-harm incidence rates by gender in Iran among individuals aged 10–39 years, 1990–2019
title_short Age-period-cohort analysis of self-harm incidence rates by gender in Iran among individuals aged 10–39 years, 1990–2019
title_sort age period cohort analysis of self harm incidence rates by gender in iran among individuals aged 10 39 years 1990 2019
topic APC analysis
Self-harm
Trends
Suicide
Incidence rates
Iran
url https://doi.org/10.1038/s41598-025-85861-y
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