Low levels of peripheral CD161++CD8+ mucosal associated invariant T (MAIT) cells are found in HIV and HIV/TB co-infection.

Low levels of peripheral CD161++CD8+ mucosal associated invariant T (MAIT) cells are found in HIV and HIV/TB co-infection.

<h4>Background</h4>High expression of CD161 on CD8+ T cells is associated with a population of cells thought to play a role in mucosal immunity. We wished to investigate this subset in an HIV and Mycobacterium tuberculosis (MTB) endemic African setting.<h4>Methods</h4>A flow...

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Main Authors: Emily B Wong, Ngomu Akeem Akilimali, Pamla Govender, Zuri A Sullivan, Cormac Cosgrove, Mona Pillay, David M Lewinsohn, William R Bishai, Bruce D Walker, Thumbi Ndung'u, Paul Klenerman, Victoria O Kasprowicz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0083474&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0083474&type=printable

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