Mendelian randomization study reveals the causal effect of sex hormone binding globulin on osteoporosis

Abstract Multiple observational studies have reported the relationship between circulating SHBG level and bone health. However, their results were inconclusive, in this research we aim to exam the relationship by two-sample Mendelian randomization. Several quality control steps were taken in our ana...

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Bibliographic Details
Main Authors: Guo-Si-Lang Zuo, Yu Huang, Ze Wang, Hong Wang, Fashuai Wu
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Musculoskeletal Disorders
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Online Access:https://doi.org/10.1186/s12891-025-08956-7
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