Reprogramming energy homeostasis in children with overweight through cognitive training and social interaction. A study protocol to estimate leptin sensitivity

Reprogramming energy homeostasis in children with overweight through cognitive training and social interaction. A study protocol to estimate leptin sensitivity

Leptin is a hormone secreted by adipocytes in proportion to the size of adipose tissue. By acting on its receptor, LepRb, primarily expressed in the hypothalamus, leptin promotes a negative energy balance by strongly suppressing appetite and stimulating energy expenditure. The majority of patients w...

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Bibliographic Details
Main Authors: Valentina Russo, Deny Menghini, Marco Mainardi, Danilo Fintini, Alessia Aureli, Nicoletta Gianni, Lucilla Ravà, Maria Alessia Rea, Gabriele Scozia, Chiara Spiezia, Gaia Scabia, Giulia Furini, Stefano Vicari, Stefano Cianfarani, Margherita Maffei, Melania Manco
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Endocrinology
Subjects:
childhood obesity
childhood overweight
cognitive training
social training
environmental enrichment
leptin
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2025.1606132/full
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https://www.frontiersin.org/articles/10.3389/fendo.2025.1606132/full

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