The NONO protein regulates nonclassical DNA structure: Effects on circadian genes and DNA damage

The NONO protein regulates nonclassical DNA structure: Effects on circadian genes and DNA damage

Summary: The DBHS protein family of Nono, PSPC1, and SFPQ regulates diverse aspects of RNA metabolism. Whether these proteins share similar functions is currently unknown. In mouse embryonic fibroblasts (MEFs), we observed around 2000 circadian and non-circadian genes regulated by Nono and PSPC1, wi...

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Bibliographic Details
Main Authors: Ermanno Moriggi, Melissa Pisteljic, Alex Rosi-Andersen, Lennart Opitz, Abdelhalim Azzi, Steven A. Brown
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:iScience
Subjects:
Nucleic acids
Properties of biomolecules
Molecular mechanism of gene regulation
Molecular interaction
Transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225006698
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