Melting curve analyses in the quantitative real-time polymerase chain reaction of methylated/non-methylated DNA toward the detection of oral cancer using gargle fluid

Melting curve analyses in the quantitative real-time polymerase chain reaction of methylated/non-methylated DNA toward the detection of oral cancer using gargle fluid

The early detection and early treatment of oral cancer are of paramount importance for improving the patients' prognoses. Our group previously reported a noninvasive test for oral cancer that uses a commercially available methylation-specific multiple ligation-dependent probe amplification (MS-...

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Bibliographic Details
Main Authors: Yusaku Noma, Hayate Sawayama, Kouta Yamashiro, Keitaro Nishi, Haruka Yoshinaga, Ryota Takaoka, Tsuyoshi Sugiura, Tomonori Sasahira, Tomofumi Hamada, Yasuo Suda, Tatsuo Okui
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Heliyon
Subjects:
Quantitative real-time PCR
Melting curve analysis
Gargle fluid
Prediction
Oral cancer
Oral squamous cell carcinoma
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844025006668
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