Hepatic irradiation persistently eliminates liver resident NK cells.

Hepatic irradiation persistently eliminates liver resident NK cells.

Hepatic irradiation for the treatment of hepatobiliary malignancies often indirectly damages liver tissue and promotes the development of liver fibrosis. However, little is known concerning the effects of hepatic irradiation on the liver immune system, including natural killer (NK) cells. The aim of...

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Bibliographic Details
Main Authors: Ryosuke Nakano, Masahiro Ohira, Takuya Yano, Yuki Imaoka, Yuka Tanaka, Hideki Ohdan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://storage.googleapis.com/plos-corpus-prod/10.1371/journal.pone.0198904/1/pone.0198904.pdf?X-Goog-Algorithm=GOOG4-RSA-SHA256&X-Goog-Credential=wombat-sa%40plos-prod.iam.gserviceaccount.com%2F20210218%2Fauto%2Fstorage%2Fgoog4_request&X-Goog-Date=20210218T134435Z&X-Goog-Expires=3600&X-Goog-SignedHeaders=host&X-Goog-Signature=b1e95635a5aed901bfbc1cbbcf4a155dbbcf75212ddc130c3cff2f2d0abb9761519be9c5889920702b8b486b5975eb0f8ea40e312a75a6a568f2da007f012dd9a29e8816bcdb7b6ae8e79cd1e48d483d0df2c84cfd985533bea97e99bd403c36f4d7bd543fa700adc653a0e8ffe854ac2bd46c32885d393f2b8f21d09f5df01f98a1ccad2ffa00d3042122fd91b908dddffd0bb99935be017d75fa045b6dbb0e376a1fa4672a03310b9921ef7b99051fdc57f4210c46abc17428f2d02beee3b0f3ee91f924c209780e15e82d9c43a9493288ed04caf9f4575de163ad817a5a38f59c59615f49d30f839c1fc37b5064abdb9ce93f6db9fb811911576fe229c382
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