Insights into the gut-liver axis: mechanisms and emerging therapies in hepatocellular carcinoma

Insights into the gut-liver axis: mechanisms and emerging therapies in hepatocellular carcinoma

The gut-liver axis is a multifaceted system where chemical and biological interactions between gut microbiota-derived metabolites and the liver significantly influence the development and progression of hepatocellular carcinoma Metabolites such as lipopolysaccharide (LPS), bile acids (BAs), and shor...

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Bibliographic Details
Main Authors: Yongjian Hu, Mingming Gao, Jiajin Chenghuang, Rui Bao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Pharmacology
Subjects:
gut-liver axis
hepatocellular carcinoma
gut microbiota-derived metabolites
tumor microenvironment
therapeutic interventions
multi-omics analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1595853/full
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https://www.frontiersin.org/articles/10.3389/fphar.2025.1595853/full

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