Secondary lesions and sensitivity to signaling inhibitors in iAMP21 acute lymphoblastic leukemia

Abstract Intrachromosomal amplification of chromosome 21 (iAMP21) B‐cell precursor acute lymphoblastic leukemia (BCP‐ALL) in children is a high‐risk subtype for which targeted drugs are lacking. In this study, we determined the frequency of secondary lesions in 28 iAMP21 BCP‐ALL patient samples and...

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Bibliographic Details
Main Authors: Femke M. Hormann, Anna Østergaard, Stijn van denBroek, Aurélie Boeree, Cesca van deVen, Gabriele Escherich, Edwin Sonneveld, Judith M. Boer, Monique L. den Boer
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:HemaSphere
Online Access:https://doi.org/10.1002/hem3.70069
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