Unveiling the impact of bisphenol a exposure on gene expression and immune response in diabetic nephropathy through integrative toxicogenomics and molecular dynamics approaches

Unveiling the impact of bisphenol a exposure on gene expression and immune response in diabetic nephropathy through integrative toxicogenomics and molecular dynamics approaches

Abstract Background Bisphenol A (BPA) exposure has been implicated in various health issues, including diabetic nephropathy (DN). Understanding the molecular mechanisms underlying BPA-induced DN is crucial for developing effective therapeutic strategies. Methods We analyzed the dataset GSE96804 to i...

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Bibliographic Details
Main Authors: Yan Zhang, Shan Lu, Yijun Dong, Jin Shang
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Diabetology & Metabolic Syndrome
Subjects:
Diabetic nephropathy
Bisphenol a
Immune cell infiltration
Bioinformatics
Machine learning
Molecular docking
Online Access:https://doi.org/10.1186/s13098-025-01874-7
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https://doi.org/10.1186/s13098-025-01874-7

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