Cutting Edge PBPK Models and Analyses: Providing the Basis for Future Modeling Efforts and Bridges to Emerging Toxicology Paradigms
Physiologically based Pharmacokinetic (PBPK) models are used for predictions of internal or target dose from environmental and pharmacologic chemical exposures. Their use in human risk assessment is dependent on the nature of databases (animal or human) used to develop and test them, and includes ex...
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Main Authors: | Jane C. Caldwell, Marina V. Evans, Kannan Krishnan |
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Format: | Article |
Language: | English |
Published: |
Wiley
2012-01-01
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Series: | Journal of Toxicology |
Online Access: | http://dx.doi.org/10.1155/2012/852384 |
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