Combination of cerium oxide nanoparticles and antimalarial drug chloroquine: characterization and anti-cancer potential for triple negative breast cancer

Combination of cerium oxide nanoparticles and antimalarial drug chloroquine: characterization and anti-cancer potential for triple negative breast cancer

Triple negative breast cancer (TNBC) is highly aggressiveness, has a poor prognosis, and standard therapy is often associated with adverse effects. As drug repurposing and nanomedicine have gained huge interest in cancer therapy, the effect of the antimalarial drug chloroquine (CQ) in combination wi...

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Bibliographic Details
Main Authors: Chantal-Kristin Wenzel, Elayaraja Kolanthai, Craig Neal, Claudia Wyrich, Andrea Borchardt, Claudia von Montfort, Nahal Brocke-Ahmadinejad, Sudipta Seal, Peter Brenneisen
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Materials & Design
Subjects:
Cerium oxide nanoparticles
Chloroquine
Triple negative breast cancer
2D cell culture
3D spheroid culture
Selective cytotoxicity
Online Access:http://www.sciencedirect.com/science/article/pii/S0264127525005994
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