Towards a more objective and high-throughput spheroid invasion assay quantification method

Abstract Multicellular spheroids embedded in 3D hydrogels are prominent in vitro models for 3D cell invasion. Yet, quantification methods for spheroid cell invasion that are high‐throughput, objective and accessible are still lacking. Variations in spheroid sizes and the shapes of the cells within r...

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Bibliographic Details
Main Authors: Rozanne W. Mungai, Roger J. Hartman, Grace E. Jolin, Kevin W. Piskorowski, Kristen L. Billiar
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-82191-3
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