An integrated multi-mode detection platform based on CRISPR/Cas 12a and aptamers for ultra-sensitive identification of sulfamethazine and genes associated with sulfonamide resistance

An integrated multi-mode detection platform based on CRISPR/Cas 12a and aptamers for ultra-sensitive identification of sulfamethazine and genes associated with sulfonamide resistance

Abstract The production and buildup of sulfamethazine (SMZ) and resistance genes for sulfonamide antibiotics (sul 1) pose a serious risk to environmental and public health safety. Creating advanced sensing systems that are both highly sensitive and selective for the prolonged observation of SMZ conc...

Full description

Saved in:
Bibliographic Details
Main Authors: Tao Zhang, Zongwu Meng, Haoyu Yu, Zerun Zhang, Guiling Liu, Anqi Qiu, Wanshu Zheng, Ping Ding, Tianhan Kai
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Journal of Nanobiotechnology
Subjects:
Nanozyme
Magnetic separation
Aptamer
CRISPR/Cas12a
SMZ
Sul1
Online Access:https://doi.org/10.1186/s12951-025-03463-2
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1186/s12951-025-03463-2

Similar Items