Exploring the tumor microenvironment in diffuse intrinsic pontine glioma: immunological insights and therapeutic challenges

Diffuse intrinsic pontine glioma (DIPG) is a rare and highly aggressive pediatric brain tumor with a median survival of less than 12 months. The tumor arises in the pons, making surgical resection unfeasible and limiting treatment options to palliative radiation, which offers minimal survival benefi...

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Bibliographic Details
Main Authors: An Coosemans, Esther Hulleman, Bieke Van den Ende, Matteo Riva, Frederik De Smet, Sandra Jacobs
Format: Article
Language:English
Published: BMJ Publishing Group 2025-06-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/13/6/e012009.full
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