Breast cancer patient-derived scaffolds enhance the understanding of PD-L1 regulation and T cell cytotoxicity
Abstract Recent advances as well as obstacles for immune-based cancer treatment strategies, highlight the notable impact of patient cancer microenvironments on the immune cells and immune targets. Here, we use patient-derived scaffolds (PDS) generated from 110 primary breast cancers to monitor the i...
Saved in:
| Main Authors: | Elena Garre, Sara Rhost, Anna Gustafsson, Louis Szeponik, Thais Fenz Araujo, Marianne Quiding-Järbrink, Khalil Helou, Anders Ståhlberg, Göran Landberg |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-04-01
|
| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-025-08054-3 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Cytotoxicity of Polymer Scaffolds Suitable for Manufacturing of Small-Diameter Vascular Grafts
by: E. A. Velikanova, et al.
Published: (2024-06-01) -
Synthesis and Cytotoxic Activity of a New Family of α-Hydroxyphosphonates with the Benzothiophene Scaffold
by: Mátyás Milen, et al.
Published: (2025-06-01) -
Infiltration of CD8+ cytotoxic T-cells and expression of PD-1 and PD-L1 in ovarian clear cell carcinoma
by: Mengdi Fu, et al.
Published: (2025-02-01) -
Designing Smartly: Understanding the Crystallinity of Melt Electrowritten Scaffolds
by: Piotr Stanisław Zieliński, et al.
Published: (2025-04-01) -
Targeting and cytotoxicity of chimeric antigen receptor T cells grafted with PD1 extramembrane domain
by: Ang Zhang, et al.
Published: (2023-09-01)