CD73-Dependent Regulation of Interferon AlphaA and Interleukin-10 in the Inflamed Mucosa

The ecto-5'-nucleotidase, CD73, catalyzes the rate-limiting step in the phosphohydrolysis of ATP to adenosine, and is a critical regulator of the balance between adenosine and its nucleotide precursors. Each of these classes of mediators signal through their independent receptor families to reg...

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Bibliographic Details
Main Authors: Ilya Sotnikov, Nancy A. Louis
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/tsw.2010.203
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