Nanoparticle-functionalized acrylic bone cement for local therapeutic delivery to spine metastases

Aim: Polymethylmethacrylate bone cement is often used to reconstruct critical-sized defects generated by the surgical resection of spinal metastases. Residual tumor cells after a resection can drive recurrence and destabilization. Doxorubicin (DOX) is a common chemotherapeutic drug with unwanted sid...

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Bibliographic Details
Main Authors: Ateeque Siddique, Mansoureh Mohseni Garakani, Megan E. Cooke, Michael H. Weber, Derek H. Rosenzweig
Format: Article
Language:English
Published: Open Exploration Publishing Inc. 2024-04-01
Series:Exploration of BioMat-X
Subjects:
Online Access:https://www.explorationpub.com/uploads/Article/A101310/101310.pdf
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