The conclusiveness of trial sequential analysis varies with estimation of between-study variance: a case study
Abstract Background Trial sequential methods have been introduced to address issues related to increased likelihood of incorrectly rejecting the null hypothesis in meta-analyses due to repeated significance testing. Between-study variance (τ2) and its estimate ( $$\widehat{\tau }$$ τ ^ 2) play a cru...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-04-01
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| Series: | BMC Medical Research Methodology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12874-025-02545-x |
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