Single-cell analysis of gene regulatory networks in the mammary glands of P4HA1-knockout mice.
Prolyl hydroxylation, catalyzed by collagen prolyl 4-hydroxylase (P4H), is a crucial post-translational modification involved in collagen biosynthesis. P4HA1, an isoform of P4H, plays a prominent role in stabilizing hypoxia-inducible factor-1α (HIF-1α). P4HA1 is frequently upregulated in highly aggr...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2025-07-01
|
| Series: | PLoS Genetics |
| Online Access: | https://doi.org/10.1371/journal.pgen.1011505 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|