Human platelet lysate enhances small lipid droplet accumulation of human MSCs through MAPK phosphorylation

Human platelet lysate enhances small lipid droplet accumulation of human MSCs through MAPK phosphorylation

Abstract Background Human platelet lysate (hPL) has emerged as a promising serum substitute to enhance the self-renewal and multipotency of human mesenchymal stem cells (MSCs). Despite its potential, the specific biological mechanisms by which hPL influences MSC phenotypes remain inadequately unders...

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Bibliographic Details
Main Authors: Ping Du, Xuelian Tao, Javad Harati, Yue Shi, Liang Xiao, Xian Li, Haobo Pan, Peng-Yuan Wang
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Stem Cell Research & Therapy
Subjects:
Human platelet lysate
Mesenchymal stem cell (MSC)
Focal adhesion
Lipid droplet
MAPK phosphorylation
Online Access:https://doi.org/10.1186/s13287-024-04085-5
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https://doi.org/10.1186/s13287-024-04085-5

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