Fast noisy long read alignment with multi-level parallelism

Fast noisy long read alignment with multi-level parallelism

Abstract Background The advent of Single Molecule Real-Time (SMRT) sequencing has overcome many limitations of second-generation sequencing, such as limited read lengths, PCR amplification biases. However, longer reads increase data volume exponentially and high error rates make many existing alignm...

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Bibliographic Details
Main Authors: Zeyu Xia, Canqun Yang, Chenchen Peng, Yifei Guo, Yufei Guo, Tao Tang, Yingbo Cui
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Bioinformatics
Subjects:
Sequence alignment
SMRT
Parallel processing
Vector-level parallelization
MPI
Heterogeneous parallelization
Online Access:https://doi.org/10.1186/s12859-025-06129-w
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https://doi.org/10.1186/s12859-025-06129-w

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