Copper excess induces autophagy dysfunction and mitochondrial ROS-ferroptosis progression, inhibits cellular biosynthesis of milk protein and lipid in bovine mammary epithelial cells
Excessive copper (Cu) has the potential risk to ecosystems and organism health, with its impact on dairy cow mammary glands being not well-defined. This study used a bovine mammary epithelial cell (MAC-T) model to explore how copper excess affects cellular oxidative stress, autophagy, ferroptosis, a...
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| Main Authors: | Ya Ting Fan, Dong Qiao Peng, Jing Lin Shen, Jun Hao Cui, Xin Yue Yang, Jin Ge Zhang, Yong Cheng Jin |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-02-01
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| Series: | Ecotoxicology and Environmental Safety |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0147651325001198 |
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