Clinical evaluation of HuDo-CSPG4 DNA electroporation as adjuvant treatment for canine oral malignant melanoma: comparison of two vaccination protocols

Clinical evaluation of HuDo-CSPG4 DNA electroporation as adjuvant treatment for canine oral malignant melanoma: comparison of two vaccination protocols

Canine oral malignant melanoma (OMM) is an aggressive, spontaneously occurring tumor carrying a poor to guarded prognosis and relatively limited therapeutic strategies. In this landscape, chondroitin sulfate proteoglycan (CSPG)4 represents a promising immunotherapeutic target. The objective of this...

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Main Authors: Mariateresa Camerino, Davide Giacobino, Lidia Tarone, Alfredo Dentini, Marina Martano, Emanuela Morello, Erica Ilaria Ferraris, Luca Manassero, Selina Iussich, Lorella Maniscalco, Federica Cavallo, Federica Riccardo, Paolo Buracco
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Veterinary Quarterly
Subjects:
Canine oral malignant melanoma
CSPG4
HuDo-CSPG4
DNA electroporation
adjuvant immunotherapy
Online Access:https://www.tandfonline.com/doi/10.1080/01652176.2025.2473717
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https://www.tandfonline.com/doi/10.1080/01652176.2025.2473717

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