Target Trial Emulation of the Modified Vaccinia Ankara-Bavarian Nordic Vaccine for Pre-Exposure Mpox Prevention in At-Risk Populations

Target Trial Emulation of the Modified Vaccinia Ankara-Bavarian Nordic Vaccine for Pre-Exposure Mpox Prevention in At-Risk Populations

<b>Background:</b> The MVA-BN vaccine is considered effective for preventing mpox in key populations, based on observational studies, though no randomized trials have yet confirmed its effectiveness. Observational studies published to date rely on retrospective analyses of routine data,...

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Main Authors: Clara Suñer, Roser Escrig-Sarreta, Cristina Galván-Casas, Eduardo Matos, Amanda Gabster, Marcelo Wolff, Dan Ouchi, Andrea Alemany, Hugo Sánchez, Sandra Huaman, Dixennia Bejarano, Lourdes Carrés-Esteve, Cristina Santiago-Fernández, Javier Corral-Rubio, Adrià Mendoza, Àngel Rivero, Vicente Descalzo, Eva Orviz, Héctor Martínez-Riveros, Leonardo Méndez-Boo, Carmen Cabezas, Araceli Arce-Arnáez, Michael Marks, Oriol Mitjà, REMAIN Study Group
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Vaccines
Subjects:
mpox
vaccine
MVA-BN
efficacy
safety
target trial emulation
Online Access:https://www.mdpi.com/2076-393X/13/6/594
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