Triphenyl phosphate induces lipid metabolism disorder and promotes obesity through PI3K/AKT signaling pathway

Triphenyl phosphate induces lipid metabolism disorder and promotes obesity through PI3K/AKT signaling pathway

Triphenyl phosphate (TPHP) is a widely used organic phosphate flame retardant that has been reported as a potential environmental obesogen. However, the potential impact and mechanism of action of TPHP on adipose tissue are still unclear. This study investigates the potential impact of TPHP on lipid...

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Bibliographic Details
Main Authors: Tianlan Li, Yiwa Liu, Jingyi Cao, Xianzhu Lu, Yinghan Lu, Yuhan Wang, Chunmei Zhang, Meifen Wu, Song Deng, Li Li, Ming Shi
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Environment International
Subjects:
Triphenyl phosphate
3T3-L1 preadipocytes
Lipid metabolism
Adipogenic differentiation
PI3K/AKT signaling pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S0160412025001795
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http://www.sciencedirect.com/science/article/pii/S0160412025001795

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