Co-design of a routine clinical review to improve the safety of high dose radical cure treatment for Plasmodium vivax malaria: findings from Cambodia and Ethiopia

Co-design of a routine clinical review to improve the safety of high dose radical cure treatment for Plasmodium vivax malaria: findings from Cambodia and Ethiopia

Abstract Background Low dose primaquine regimens are widely used to treat Plasmodium vivax malaria, but they have limited efficacy and effectiveness. Short courses with higher daily doses as well as single dose tafenoquine have the potential to improve effectiveness but can increase the risk of adve...

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Main Authors: Sarah A. Cassidy-Seyoum, Muthoni Mwaura, Keoratha Chheng, Muhaba Kejela, Kansite Gellebo Korra, Tsegaberhan Wodaj, Tamiru Shibiru Degaga, Michelle S. Hsiang, Lorenz von Seidlein, Rupam Tripura, Bipin Adhikari, Benedikt Ley, Dysoley Lek, Ric N. Price, Nora Engel, Kamala Thriemer
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Malaria Journal
Subjects:
Malaria
Vivax malaria
Radical cure
Novel treatment
Pharmacovigilance
Treatment monitoring
Online Access:https://doi.org/10.1186/s12936-025-05425-3
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https://doi.org/10.1186/s12936-025-05425-3

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