Cytokine profiling identifies circulating IL-2, IL23 and sPD-L1 as prognostic biomarkers for treatment outcomes in non-small cell lung cancer patients undergoing anti-PD1 therapy

Cytokine profiling identifies circulating IL-2, IL23 and sPD-L1 as prognostic biomarkers for treatment outcomes in non-small cell lung cancer patients undergoing anti-PD1 therapy

BackgroundThis study investigates the predictive potential of circulating cytokines for response and survival outcomes in patients with advanced non-small cell lung cancer (NSCLC) undergoing immune checkpoint inhibitor (ICI) therapy.Materials and methodsA cohort of 64 patients with advanced NSCLC re...

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Bibliographic Details
Main Authors: Kriti Jain, Anika Goel, Deepa Mehra, Deepak Kumar Rathore, Akshay Binayke, Shyam Aggarwal, Surajit Ganguly, Amit Awasthi, Evanka Madan, Nirmal Kumar Ganguly
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Oncology
Subjects:
non-small cell lung cancer (NSCLC)
immune checkpoint inhibitors (ICIs)
IL-2
sPD-L1
IL-23
biomarkers
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1628379/full
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https://www.frontiersin.org/articles/10.3389/fonc.2025.1628379/full

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