Fabrication and Optimization of a Silodosin In Situ-Forming PLGA Implants for the Treatment of Benign Prostatic Hyperplasia: In Vitro and In Vivo Study

Fabrication and Optimization of a Silodosin In Situ-Forming PLGA Implants for the Treatment of Benign Prostatic Hyperplasia: In Vitro and In Vivo Study

<b>Objectives:</b> Lower urinary tract symptoms (LUTSs) related to benign prostatic hyperplasia (BPH) are common in older men, and alpha-adrenoceptor blockers continue to be a key part of managing these symptoms. This study aimed to formulate injectable poly (lactic-co-glycolic acid) (PL...

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Main Authors: Rabab A. Husseini, Tarek M. Ibrahim, Eslam Hamed, Eman Gomaa, Mennatullah M. Faisal, Ghadeer Wan, Manna Amin, Ali M. Alkolaib, Dina M. Abdelnabi
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Pharmaceutics
Subjects:
silodosin
PLGA
in situ-forming implants
I-optimal design
benign prostatic hyperplasia
Online Access:https://www.mdpi.com/1999-4923/16/11/1364
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