Inosine Prevents Colorectal Cancer Progression by Inducing M1 Phenotypic Polarization of Macrophages

Inosine Prevents Colorectal Cancer Progression by Inducing M1 Phenotypic Polarization of Macrophages

Inosine (IS) is a naturally occurring metabolite of adenosine with potent immunomodulatory effects. This study investigates the immunomodulatory effects of inosine, particularly its ability to inhibit the development of colorectal cancer (CRC) cells CT26 through modulation of macrophage phenotypes....

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Bibliographic Details
Main Authors: Yuchen Ma, Xiaoli Qian, Qun Yu, Yadan Dong, Jiapeng Wang, Heng Liu, Huai Xiao
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Molecules
Subjects:
inosine
macrophage polarization
colorectal cancer
Online Access:https://www.mdpi.com/1420-3049/30/1/123
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