Upregulation of Nrf2 attenuates Angiostrongylus cantonensis-induced parasitic meningitis in mice

Upregulation of Nrf2 attenuates Angiostrongylus cantonensis-induced parasitic meningitis in mice

Abstract Background Angiostrongylus cantonensis is a food-borne parasite that can infect mammals, including humans, causing angiostrongyliasis. The nuclear factor E2-related factor 2 (Nrf2) is a transcription factor that plays a crucial role in the host’s antioxidant defense and inflammation mechani...

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Main Authors: Chii-Wen Chou, Chia-Chun Huang, Ke-Min Chen, Chun-I Wang, Wan-Jing Chen, Chiung-Hung Hsu, Shih-Chan Lai, Shyun Chou, Yu-Kang Chang, Kuan-Yu Lin, Chih-Hao Chiu, Cheng-You Lu
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Parasites & Vectors
Subjects:
A. cantonensis
Anti-inflammation
Antioxidant
Nrf2
Parasitic meningitis
Online Access:https://doi.org/10.1186/s13071-025-06724-z
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https://doi.org/10.1186/s13071-025-06724-z

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