Magnetic and pH sensitive nanocomposite microspheres for controlled temozolomide delivery in glioblastoma cells

Magnetic and pH sensitive nanocomposite microspheres for controlled temozolomide delivery in glioblastoma cells

Abstract Controlled drug delivery systems have been intensively researched for cancer treatment to increase precision targeting and therapeutic efficacy. In this context, novel magnetic-/pH-sensitive graphene oxide/chitosan/iron oxide magnetic nanocomposite microspheres were synthesized. Fe3O4 (IO)...

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Bibliographic Details
Main Authors: Meysam Ahmadi, Muhammad Hossein Ashoub, Kamran Heydaryan, Sanaz Abolghasemi, Elmuez A. Dawi, Ghazal khajouei, Mahnaz Amiri
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Subjects:
Glioblastoma
Magnetic Microspheres
PH-sensitive
Temozolomide
Controlled drug delivery
Online Access:https://doi.org/10.1038/s41598-024-80596-8
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https://doi.org/10.1038/s41598-024-80596-8

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