Expression analysis and possible functional roles of semaphorin/plexin/CRMP families in mouse pancreatic islets

Expression analysis and possible functional roles of semaphorin/plexin/CRMP families in mouse pancreatic islets

Abstract Semaphorins were initially identified as axon guidance molecules that were widely expressed and involved in divergent functions in various organs, including neuronal development and immunological processes. Collapsin response mediator proteins (CRMPs) are involved in the intracellular signa...

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Main Authors: Mayu Kyohara, Rie Takayanagi, Takahiro Tsuno, Esther Ong Yajima, Ryota Inoue, Naoya Yamashita, Tomoko Okuyama, Kuniyuki Nishiyama, Kohichi Matsunaga, Emi Ishida, Shuichi Ito, Yasuo Terauchi, Yoshio Goshima, Jun Shirakawa
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
Semaphorin
Plexin
CRMP-2
Glucokinase
Glucokinase activator
Diabetes
Online Access:https://doi.org/10.1038/s41598-025-95300-7
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https://doi.org/10.1038/s41598-025-95300-7

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